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https://idr.l2.nitk.ac.in/jspui/handle/123456789/13264
Title: | Synthesis of hybrid polycycles containing fused hydroxy benzofuran and 1H-indazoles via a domino cyclization reaction |
Authors: | Janardhanan, J.C. James, K. Puthuvakkal, A. Bhaskaran, R.P. Suresh, C.H. Praveen, V.K. Manoj, N. Babu, B.P. |
Issue Date: | 2019 |
Citation: | New Journal of Chemistry, 2019, Vol.43, 25, pp.10166-10175 |
Abstract: | A stoichiometry controlled domino cyclization reaction of hydrazone and p-benzoquinone to an angularly fused 3H-benzofuro[3,2-e]indazole core with an embedded oxygenated dibenzofuran framework under mild reaction conditions is disclosed. The reaction involves palladium catalyzed 5-hydroxy-1H-indazole formation followed by TFA mediated [3+2] annulation between the in situ formed 5-hydroxy-1H-indazole and p-benzoquinone. The developed method is attractive because of the concomitant formation of two heterocyclic rings with consecutive multiple bond forming events that include two C-C, one C-N and one C-O bonds. Spectroscopic and theoretical studies of the blue emissive benzofuroindazole derivatives have also been described. 2019 The Royal Society of Chemistry and the Centre National de la Recherche Scientifique. |
URI: | http://idr.nitk.ac.in/jspui/handle/123456789/13264 |
Appears in Collections: | 1. Journal Articles |
Files in This Item:
File | Description | Size | Format | |
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3 Synthesis of hybrid.pdf | 2.9 MB | Adobe PDF | View/Open |
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