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DC Field | Value | Language |
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dc.contributor.author | Sankappa, Rai, U. | |
dc.contributor.author | Isloor, A.M. | |
dc.contributor.author | shetty, P. | |
dc.contributor.author | Vijesh, A.M. | |
dc.contributor.author | Prabhu, N. | |
dc.contributor.author | Isloor, S. | |
dc.contributor.author | Thiageeswaran, M. | |
dc.contributor.author | Fun, H.-K. | |
dc.date.accessioned | 2020-03-31T08:38:55Z | - |
dc.date.available | 2020-03-31T08:38:55Z | - |
dc.date.issued | 2010 | |
dc.identifier.citation | European Journal of Medicinal Chemistry, 2010, Vol.45, 6, pp.2695-2699 | en_US |
dc.identifier.uri | http://idr.nitk.ac.in/jspui/handle/123456789/12285 | - |
dc.description.abstract | An efficient, microwave irradiated synthesis of novel chromeno[2,3-b]-pyrimidine derivatives was carried out. 2-Amino-3,4-dihydro-2H-chromene-3-carbonitrile was converted into imine using N,N-Dimethylacetaldehyde dimethylacetal to give the core intermediate, which was used for the preparation of chromenopyrimidine library, using acetic acid and different amine in microwave irradiation for 5 min. Structures of newly synthesized compounds were confirmed by spectral studies. Compound 6g was characterized by single crystal X-ray analysis. All the compounds were also screened for their anti-microbial activity. Few of the compounds are found to be potential antimicrobials. 2010 Elsevier Masson SAS. All rights reserved. | en_US |
dc.title | Novel chromeno [2,3-b]-pyrimidine derivatives as potential anti-microbial agents | en_US |
dc.type | Article | en_US |
Appears in Collections: | 1. Journal Articles |
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