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dc.contributor.authorSankappa, Rai, U.
dc.contributor.authorIsloor, A.M.
dc.contributor.authorshetty, P.
dc.contributor.authorVijesh, A.M.
dc.contributor.authorPrabhu, N.
dc.contributor.authorIsloor, S.
dc.contributor.authorThiageeswaran, M.
dc.contributor.authorFun, H.-K.
dc.date.accessioned2020-03-31T08:38:55Z-
dc.date.available2020-03-31T08:38:55Z-
dc.date.issued2010
dc.identifier.citationEuropean Journal of Medicinal Chemistry, 2010, Vol.45, 6, pp.2695-2699en_US
dc.identifier.urihttp://idr.nitk.ac.in/jspui/handle/123456789/12285-
dc.description.abstractAn efficient, microwave irradiated synthesis of novel chromeno[2,3-b]-pyrimidine derivatives was carried out. 2-Amino-3,4-dihydro-2H-chromene-3-carbonitrile was converted into imine using N,N-Dimethylacetaldehyde dimethylacetal to give the core intermediate, which was used for the preparation of chromenopyrimidine library, using acetic acid and different amine in microwave irradiation for 5 min. Structures of newly synthesized compounds were confirmed by spectral studies. Compound 6g was characterized by single crystal X-ray analysis. All the compounds were also screened for their anti-microbial activity. Few of the compounds are found to be potential antimicrobials. 2010 Elsevier Masson SAS. All rights reserved.en_US
dc.titleNovel chromeno [2,3-b]-pyrimidine derivatives as potential anti-microbial agentsen_US
dc.typeArticleen_US
Appears in Collections:1. Journal Articles

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