Please use this identifier to cite or link to this item: https://idr.l2.nitk.ac.in/jspui/handle/123456789/15714
Full metadata record
DC FieldValueLanguage
dc.contributor.authorNainegali B.S.
dc.contributor.authorIyyaswami R.
dc.contributor.authorD Belur P.
dc.date.accessioned2021-05-05T10:27:47Z-
dc.date.available2021-05-05T10:27:47Z-
dc.date.issued2020
dc.identifier.citationSeparation and Purification Technology Vol. 253 , , p. -en_US
dc.identifier.urihttps://doi.org/10.1016/j.seppur.2020.117520
dc.identifier.urihttp://idr.nitk.ac.in/jspui/handle/123456789/15714-
dc.description.abstractThe simultaneous extraction of anthocyanins (ACNs), garcinol (GL), isogarcinol (IGL) and hydroxycitric acid (HCA) from the rinds of Garcinia indica (GI) fruit and their partition behaviour in the aqueous two-phase system (ATPS) formed by 1-propanol-(NH4)2SO4 was investigated. The effect of different variables that govern the partition characteristics were studied and the amount of crude loaded into the ATPS, the concentration of 1-propanol and (NH4)2SO4 were found to be the significant variables. The Response Surface Methodology (RSM) was adopted to optimize the process variables through desirability based multi-response optimization for the partitioning of GL and IGL to the alcohol rich top phase and ACNs and HCA to the salt-rich bottom phase by considering the partitioning coefficients (K) and extraction efficiency of all the four bioactive components as responses. A ATPS consisting of 15.202% (w/w) 1-propanol, 10.242% (w/w) (NH4)2SO4 having the TLL of 28.505% (w/w) at a crude load of 25% (w/w) able to partition 97.39% GL (K = 370.770) and 92.38% IGL (K = 120.581) in the top phase and 99.19% ACNs (K = 0.080) and 99.83% HCA (K = 0.016) in the bottom phase with a purity higher than 99% by implementing secondary ATPS. © 2020 Elsevier B.V.en_US
dc.titlePartitioning of bio-active compounds from rinds of garcinia indica using aqueous two-phase system: Process evaluation and optimizationen_US
dc.typeArticleen_US
Appears in Collections:1. Journal Articles

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.